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Your doctor may also recommend other drugs. If youve always been susceptible to tension headaches pregnancy can make the problem worse. Pin On Women S Health Beta-blockers which are used to lower blood pressure can also prevent migraines and are considered relatively safe during pregnancy. . Tylenol sold as the generic acetaminophen is the safest headache medication during pregnancy and is not associated with any known birth defects according to. Rest and relax as much as possible. Some anti-nausea medications including prochlorperazine metoclopramide and diphenhydramine can also relieve migraine symptoms. Your health care provider might recommend other medications as well. Eat smaller more frequent meals to maintain your blood sugar. Remember that most expecting mothers can take acetaminophen when treating regular headaches. Acetaminophen Tylenol taking rest by sleeping high protein diet can take if you have a headache wh...